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Combination drug treatments for drug-resistant Fusarium infections

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Ray Zhang · Chantilly, Virginia
Tenth Place ($40,000) · Regeneron Science Talent Search · 2025

Abstract

Testing of combination drug treatments against drug-resistant Fusarium, a fungal genus that causes infections increasingly difficult to treat with single agents.

Why it worked
ResearchForge's reading of the public record — not the students' words, and not the judges' reasoning.

Combination therapy is the standard answer to resistance, but which combinations work is an empirical question. A systematic screen is exactly the right shape of project for it.

Key methods
  • Antifungal susceptibility testing
  • Combination drug screening
  • Resistant isolate culture
  • Synergy evaluation
What to take from this
ResearchForge's reading of the public record — not the students' words, and not the judges' reasoning. Borrow the habits and decisions, never the project itself.
  • Resistance problems usually need a combinatorial screen, so design for throughput from the start
  • Antifungal work needs a resistant isolate, not a laboratory strain, or the result does not transfer

Archive entries are summaries compiled for study. Read them for how a project was structured, argued, and defended — not as a template to reproduce. Copying someone else's project is the one thing that will end yours.

Compiled by ResearchForge from the Society for Science public award announcement linked on this record. Names, hometowns, project titles and reported results are as published. The "why it worked" and "what to take from this" notes are ResearchForge's editorial reading of that public record — they are not statements by the students and not the judges' rationale. All rights to the original projects remain with their authors; no project materials are rehosted here.