A fruit fly model of STAC3 disorder
Ava Grace Cummings
First place · Regeneron STS 2025
Both adult flies and larvae showed improved movement under treatment.
- rare-disease
- drosophila
- myopathy
- +2
What strong projects actually look like — the question they asked, the design that survived review, and the one decision that made the difference.
Archive entries are summaries compiled for study. Read them for how a project was structured, argued, and defended — not as a template to reproduce. Copying someone else's project is the one thing that will end yours.
9 projects in Biology
Ava Grace Cummings
First place · Regeneron STS 2025
Both adult flies and larvae showed improved movement under treatment.
Aakash Manaswi
Third place · Regeneron ISEF 2026
Reported mite elimination as effective as pesticide treatment, without pesticide residues, alongside improved hive health measures.
Evan Morris
Third place · Regeneron ISEF 2026
Reported a 70.1% reduction in seizure recurrence.
Logan Lee
Third place · Regeneron STS 2025
Bacterial transplants used to raise the survival rate of sterile male mosquitoes, addressing the weak point of the sterile insect technique: released males that die before they can compete for mates.
Ray Zhang
Finalist · Regeneron STS 2025
Testing of combination drug treatments against drug-resistant Fusarium, a fungal genus that causes infections increasingly difficult to treat with single agents.
Melody Heeju Hong
Finalist · Regeneron STS 2025
A statistical model for locating trans-methylation quantitative trait loci — genetic variants that influence DNA methylation at distant sites rather than nearby ones.
Tanishka Balaji Aglave
Third place · Regeneron ISEF 2024
A natural alternative treatment for citrus greening, using curry leaf tree extract injected directly into tree trunks. Citrus greening has no cure and has reshaped citrus agriculture wherever it has spread.
Maddux Alexander Springer
Third place · Regeneron ISEF 2024
Field research on fibropapillomatosis in green sea turtles, examining its relationship to wastewater input, invasive algae, and the amino acid arginine as a possible mechanistic link.
Pannathorn Siri, Poon Trakultangmun, and Teepakorn Keawumdee
First place · Regeneron ISEF 2023
Reported a five-fold increase in lacewing survival rate.