Skip to content
Join

Winning projects

What strong projects actually look like — the question they asked, the design that survived review, and the one decision that made the difference.

Archive entries are summaries compiled for study. Read them for how a project was structured, argued, and defended — not as a template to reproduce. Copying someone else's project is the one thing that will end yours.

20 projects

advanced

RetinaMind

Edward Kang

First place · Regeneron STS 2026

An AI screening tool that reads retinal images for patterns associated with autism and ADHD, paired with cellular models built to examine the genetic factors that might explain the association.

  • medical-imaging
  • machine-learning
  • retina
  • +2
Biomedical & Health ScienceTranslational Medical Science
advanced

A fruit fly model of STAC3 disorder

Ava Grace Cummings

First place · Regeneron STS 2025

Both adult flies and larvae showed improved movement under treatment.

  • rare-disease
  • drosophila
  • myopathy
  • +2
BiologyGenetics
advanced

A compression model for protein structure comparison

Jerry Xu

Fourth place · Regeneron STS 2026

A model that compresses a protein's molecular features into a compact numerical representation, so that structures can be compared efficiently without losing the features that matter.

  • protein-structure
  • representation-learning
  • bioinformatics
  • +1
Computer ScienceComputational Biology and Bioinformatics
advanced

Temperley-Lieb Diagrams for Quantum Systems

Rachel Chen

Third place · Regeneron STS 2026

A diagrammatic representation of interacting quantum particle systems, using point-and-line diagrams to make the influence of magnetic fields visible in the structure itself.

  • quantum-mechanics
  • diagrammatic-algebra
  • temperley-lieb
  • +1
Mathematics
advanced

The unrestricted finite factorization property

Jonathan Du

Finalist · Regeneron STS 2026

Work in factorization theory on algebraic systems whose elements may factor in many ways or in none, extending the theory of when factorizations are finite.

  • abstract-algebra
  • factorization
  • ring-theory
  • +1
MathematicsPure Mathematics
advanced

A bound on similar structures in 3-uniform hypergraphs

Owen Jianwen Zhang

Second place · Regeneron STS 2025

A proof establishing a maximum for how many 3-uniform hypergraphs can share a structure while differing in their connections, resolving a question that had stood open, with applications in computer science.

  • combinatorics
  • hypergraphs
  • extremal-combinatorics
  • +1
Mathematics
advanced

Bacterial transplants to improve sterile male mosquito survival

Logan Lee

Third place · Regeneron STS 2025

Bacterial transplants used to raise the survival rate of sterile male mosquitoes, addressing the weak point of the sterile insect technique: released males that die before they can compete for mates.

  • vector-control
  • mosquitoes
  • microbiome
  • +2
BiologyMicrobiology