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Winning projects

What strong projects actually look like — the question they asked, the design that survived review, and the one decision that made the difference.

Archive entries are summaries compiled for study. Read them for how a project was structured, argued, and defended — not as a template to reproduce. Copying someone else's project is the one thing that will end yours.

10 projects

advanced

A fruit fly model of STAC3 disorder

Ava Grace Cummings

First place · Regeneron STS 2025

Both adult flies and larvae showed improved movement under treatment.

  • rare-disease
  • drosophila
  • myopathy
  • +2
BiologyGenetics
advanced

A bound on similar structures in 3-uniform hypergraphs

Owen Jianwen Zhang

Second place · Regeneron STS 2025

A proof establishing a maximum for how many 3-uniform hypergraphs can share a structure while differing in their connections, resolving a question that had stood open, with applications in computer science.

  • combinatorics
  • hypergraphs
  • extremal-combinatorics
  • +1
Mathematics
advanced

Bacterial transplants to improve sterile male mosquito survival

Logan Lee

Third place · Regeneron STS 2025

Bacterial transplants used to raise the survival rate of sterile male mosquitoes, addressing the weak point of the sterile insect technique: released males that die before they can compete for mates.

  • vector-control
  • mosquitoes
  • microbiome
  • +2
BiologyMicrobiology